Adiponectine

Adiponectin

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

Adiponectin is a protein hormone secreted exclusively by adipose (fat) tissue. It plays a vital role in regulating metabolism and energy homeostasis, as well as having anti-inflammatory and cardioprotective effects.

Structure and Functions of Adiponectin

Adiponectin is a relatively large protein composed of 244 amino acids. It exists in several oligomeric forms, including trimers, hexamers, and higher-order multimeric structures. These different forms exhibit varying biological activities and affinities for receptors.

Adiponectin has numerous beneficial effects on the body, including improving insulin sensitivity, reducing inflammation, and protecting against cardiovascular diseases. It also plays a role in regulating energy balance and glucose and lipid metabolism.

The Role of Adiponectin in Diagnostics

Adiponectin is a hormone secreted by adipose tissue, and its levels in the blood serve as an important diagnostic marker for various health conditions. Adiponectin plays a crucial role in regulating glucose and lipid metabolism, as well as exerting anti-inflammatory and anti-atherogenic effects.

Indications for Adiponectin Testing

Adiponectin testing is recommended in the following situations:

• Evaluation of metabolic disorders: Low levels of adiponectin are associated with obesity, insulin resistance, type 2 diabetes, and metabolic syndrome. Assessing adiponectin levels can help in the diagnosis and management of these conditions.
• Cardiovascular disease risk assessment: Adiponectin has cardioprotective properties, and low levels have been linked to an increased risk of cardiovascular diseases, such as coronary artery disease and hypertension.
• Monitoring of obesity and weight management: Adiponectin levels are inversely correlated with body fat percentage. Measuring adiponectin can provide insights into the effectiveness of weight loss interventions and the associated metabolic improvements.
• Evaluation of inflammatory conditions: Adiponectin exhibits anti-inflammatory properties, and its levels may be altered in inflammatory conditions like rheumatoid arthritis and inflammatory bowel diseases.

Preparation for the Adiponectin Test Procedure

The procedure for giving a blood sample to determine the level of adiponectin is relatively simple and does not require special preparation measures. However, there are a few recommendations that should be considered:

• Dietary regimen: In most cases, the blood test for adiponectin can be taken either fasting or after a meal. However, in some situations (e.g., during a comprehensive biochemical blood test), it may be required to observe an 8-12 hour fast before giving blood.
• Avoiding physical exertion: You should avoid intense physical exertion on the day before the test, as it may affect the test results.
• Avoiding alcohol and smoking: It is recommended to refrain from consuming alcohol and smoking for a day before the test, as these can affect the level of adiponectin and other blood parameters.
• Maintaining hydration: Maintaining proper hydration is essential for facilitating the blood collection procedure. Inadequate fluid intake can make the venipuncture procedure more difficult.
• Informing the doctor about medication intake: Some medications may affect the level of adiponectin and other blood parameters. Therefore, it is crucial to inform the doctor about all medications being taken.

Adiponectin Test Procedure

Blood collection for the adiponectin test is typically done from a vein in the bend of the elbow. The procedure takes a few minutes and is performed by a medical professional. After the venipuncture, there may be a minor bleeding or bruising, which usually resolves on its own within a few days.

Sources:

https://en.wikipedia.org/wiki/Adiponectin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8066826/
https://my.clevelandclinic.org/health/articles/22439-adiponectin
https://www.nature.com/articles/s42255-019-0041-z
https://www.ncbi.nlm.nih.gov/books/NBK537041/
https://pubmed.ncbi.nlm.nih.gov/33088464/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486142/

IMPORTANT!

It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any pain or an exacerbation of a condition, it is essential to consult a doctor for diagnostic tests and proper treatment. Only a qualified medical professional can make an accurate diagnosis and determine the appropriate treatment. For the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may use varying methods and units of measurement for similar tests.