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Total bilirubin

70.00 MDL

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

Total bilirubin is a laboratory marker that reflects bilirubin metabolism in the body. Bilirubin is produced during the natural breakdown of red blood cells and is normally processed by the liver before being excreted in bile.

Measurement of total bilirubin is used to evaluate liver function, assess the condition of the biliary tract, and detect increased red blood cell destruction (hemolysis). It is one of the core biochemical blood tests and helps identify disorders of bilirubin metabolism.

Indications

The test is recommended for individuals with:

  • yellowing of the skin or the whites of the eyes (jaundice);
  • dark urine or pale-colored stools;
  • pain or discomfort in the right upper abdomen;
  • suspected liver disease;
  • suspected gallbladder or biliary tract disorders;
  • suspected hemolysis (increased destruction of red blood cells);
  • monitoring of liver diseases;
  • routine health check-ups and biochemical blood testing.

What does the test show?

Total bilirubin reflects the combined concentration of direct (conjugated) and indirect (unconjugated) bilirubin in the blood.

Elevated total bilirubin levels may occur in liver diseases, impaired bile flow, increased destruction of red blood cells (hemolysis), and certain inherited disorders of bilirubin metabolism, such as Gilbert syndrome.

To determine the underlying cause of elevated total bilirubin, your physician may recommend measuring direct and indirect bilirubin, as well as additional laboratory and imaging studies.

Procedure

The test is performed using a venous blood sample.

The laboratory measures the concentration of total bilirubin in blood serum using a biochemical method. The test is rapid, safe, and routinely included in standard biochemical blood testing.

 

Sources:

https://medlineplus.gov/lab-tests/bilirubin-blood-test/
https://www.medicalnewstoday.com/articles/315086
https://www.healthline.com/health/high-bilirubin
https://www.webmd.com/a-to-z-guides/bilirubin-test
https://en.wikipedia.org/wiki/Bilirubin
https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=total_bilirubin_blood
https://www.mayoclinic.org/tests-procedures/bilirubin/about/pac-20393041
https://my.clevelandclinic.org/health/diagnostics/17845-bilirubin

 

IMPORTANT!

It is very important to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience pain or a worsening of your condition, it is essential to consult a doctor for diagnostic testing. Only a qualified healthcare professional can make an accurate diagnosis and determine appropriate treatment. To obtain the most accurate and consistent assessment of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may use different methods and units of measurement for similar tests.

Preparation:

For the most accurate results, it is recommended to:

  • fast for 8–12 hours before blood collection;
  • avoid alcohol and fatty foods for 24 hours before the test;
  • avoid strenuous physical activity the day before the test;
  • refrain from smoking and, if possible, avoid emotional stress for at least 30 minutes before blood collection.

Before the test, inform your physician about any medications you are taking, as some drugs may affect bilirubin levels or the interpretation of the test results.

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