Double pregnancy test I quarter (free β-hCG, PAPP-А)

Double Pregnancy Test I Quarter (Free β-hCG - PAPP-A)

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

The Double Pregnancy Test I Quarter (Free β-hCG - PAPP-A) is a screening test performed during the first trimester of pregnancy. It is designed to assess the risk of certain chromosomal abnormalities, such as Down syndrome (Trisomy 21) and Trisomy 18, in the developing fetus.

Components of the Test

The test measures the levels of two specific substances in the mother's blood:

1. Free β-hCG (Free Beta-Human Chorionic Gonadotropin): A hormone produced by the placenta during pregnancy.
2. PAPP-A (Pregnancy-Associated Plasma Protein-A): A protein produced by the placenta and the fetus.

The levels of these substances are combined with maternal age and other factors to calculate the risk of chromosomal abnormalities.

Significance of the Test

The Double Pregnancy Test I Quarter provides valuable information to expectant parents and healthcare professionals. It helps identify pregnancies that may be at an increased risk for certain chromosomal abnormalities, allowing for further diagnostic testing and timely intervention if necessary.

It is important to note that this test is a screening tool and does not provide a definitive diagnosis. If the test indicates an increased risk, further diagnostic testing, such as amniocentesis or chorionic villus sampling, may be recommended.

The Role of Double Pregnancy Test I Quarter (Free β-hCG-PAPP-A)

The Double Pregnancy Test I Quarter (Free β-hCG-PAPP-A) is an essential screening test performed during the first trimester of pregnancy. It helps assess the risk of certain chromosomal abnormalities and complications in the developing fetus. The test measures two important markers: free beta-human chorionic gonadotropin (free β-hCG) and pregnancy-associated plasma protein-A (PAPP-A).

Indications for Ordering the Test

The Double Pregnancy Test I Quarter (Free β-hCG-PAPP-A) is recommended for pregnant women to evaluate the potential risk of specific conditions, including:

• Down syndrome (Trisomy 21): This chromosomal disorder can cause intellectual disability, developmental delays, and other health issues.
• Trisomy 18 (Edwards syndrome): A severe chromosomal abnormality that can lead to intellectual disability and various physical malformations.
• Preeclampsia: A pregnancy complication characterized by high blood pressure and potential organ damage, which can be life-threatening for both the mother and the baby.

By measuring the levels of free β-hCG and PAPP-A, this test can provide valuable information about the likelihood of these conditions occurring. It is an important screening tool that aids in early detection and management of potential risks during pregnancy.

Preparation for the Double Pregnancy Test I Quarter (Free β-HCG- PAPP-A) Procedure

Prior to undergoing the Double Pregnancy Test I Quarter (Free β-HCG- PAPP-A), it is recommended to follow these guidelines:

• Maintain your regular diet: There is no need for fasting or dietary restrictions before this test.
• Avoid strenuous physical activities: It is advisable to avoid intense physical exercises a day before the test, as they may temporarily affect the results.
• Abstain from alcohol and smoking: Refrain from consuming alcohol and smoking for at least 24 hours before the test, as these substances can potentially influence the test results.
• Stay well-hydrated: Ensure adequate hydration before the test to facilitate the blood draw process.
• Disclose medication usage: Inform your healthcare provider about any medications or supplements you are currently taking, as some may affect the test results.

Procedure for the Double Pregnancy Test I Quarter (Free β-HCG- PAPP-A)

The Double Pregnancy Test I Quarter (Free β-HCG- PAPP-A) involves a simple blood draw, typically from a vein in the arm. The procedure is performed by a trained healthcare professional and takes only a few minutes. Some minor bruising or bleeding at the puncture site may occur, but it usually resolves within a few days.

Sources:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547446/
https://www.vinmec.com/en/news/health-news/in-which-week-of-pregnancy-is-the-double-test-performed/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465076/
https://www.carehospitals.com/diagnostics/double-marker-test
https://cps-check.com/double-click-test
https://www.healthline.com/health/pregnancy/double-marker-test

IMPORTANT!

It is crucial to remember that the information provided here is not intended for self-diagnosis or self-treatment. If you experience any symptoms or have a medical condition, it is essential to consult with a qualified healthcare professional for proper diagnosis and treatment. Only a qualified specialist can make an accurate diagnosis and determine the appropriate treatment plan. To ensure the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may use varying methods and units of measurement for similar tests.