Alanine aminotransferase, ALT

Alt (Alanine Aminotransferase)

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

Alanine aminotransferase (ALT), also known as Serum Glutamic Pyruvic Transaminase (SGPT), is an enzyme found primarily in the liver cells. It plays a crucial role in the metabolism of proteins and is used as a biomarker for liver health.

Functions of ALT

ALT is involved in the transfer of an amino group from alanine to alpha-ketoglutarate, a process known as transamination. This reaction is essential for the synthesis of proteins and the breakdown of amino acids. While ALT is primarily found in the liver, it is also present in smaller amounts in other tissues such as muscles, kidneys, and the heart.

Table 1: Composition of ALT

ALT is primarily found within the liver cells. When the liver is damaged or inflamed, ALT can leak into the bloodstream, causing an elevation in its serum levels. This increase in ALT levels is often an indicator of liver injury or disease.

The Role of ALT

Alanine Aminotransferase (ALT) is an enzyme found primarily in the liver cells. Its level in the blood is a significant indicator of liver health and function. ALT plays a crucial role in assessing liver damage or inflammation, as it is released into the bloodstream when liver cells are injured or destroyed.

About the ALT Test

The alanine transaminase (ALT) test is a blood test that measures the level of the ALT enzyme in the blood. ALT is an enzyme primarily found in the liver cells, and elevated levels may indicate liver damage or disease.

The ALT test is often performed as part of a panel of liver function tests, which may also include other enzymes such as aspartate transaminase (AST), alkaline phosphatase (ALP), and bilirubin. These tests help evaluate the overall health and function of the liver.

The ALT test is important because it can help detect and monitor liver diseases, such as hepatitis, cirrhosis, and liver injury caused by medications or alcohol. However, it is essential to interpret the results in conjunction with other clinical information and tests, as ALT levels alone may not provide a complete picture of the underlying condition.

Sources:

https://my.clevelandclinic.org/health/diagnostics/22028-alanine-transaminase-alt
https://www.verywellhealth.com/liver-enzymes-1759916
https://en.wikipedia.org/wiki/Alanine_transaminase
https://www.healthline.com/health/alt
https://medlineplus.gov/lab-tests/alt-blood-test/
https://www.webmd.com/digestive-disorders/alanine-aminotransferase-test
https://www.healthline.com/health/how-to-lower-alt

IMPORTANT!

It is crucial to remember that the information provided here is not intended for self-diagnosis or self-treatment. If you experience pain or symptoms, it is essential to consult a healthcare professional for proper diagnosis and treatment. Only a qualified specialist can accurately diagnose and determine the appropriate course of action. For the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory. Different laboratories may use varying methods and units of measurement for similar tests.