Soluble fibrin monomer complexes (SFMC)
We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.
Soluble fibrin monomer complexes (SFMCs) are complexes formed during the conversion of fibrinogen into fibrin and serve as a marker of activation of the blood coagulation process. SFMC testing may provide information about fibrin formation activation and contribute to the assessment of the coagulation system in certain clinical situations.
An increased SFMC level may be associated with activation of blood coagulation and fibrin formation and should be interpreted together with clinical data and other laboratory test results.
Indications
- assessment of coagulation system activation;
- suspected conditions associated with increased fibrin formation;
- assessment of patients at risk of coagulation disorders;
- monitoring of conditions associated with coagulation activation, as recommended by a physician;
- comprehensive assessment of hemostasis together with other coagulation tests;
- other clinical situations, as recommended by a physician.
Procedure
The test is performed using a venous blood sample. The sample is processed in the laboratory using a specific method to determine soluble fibrin monomer complexes.
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975135/
https://ashpublications.org/blood/article/136/Supplement%201/27/472810/Evaluation-of-Soluble-Fibrin-Monomer-Complex-in
https://en.wikipedia.org/wiki/Fibrin_monomer
https://onlinelibrary.wiley.com/doi/10.1111/ejh.13738
IMPORTANT!
It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any symptoms or a worsening of a condition, it is essential to consult a healthcare professional for proper diagnostic tests and treatment recommendations. Only a qualified specialist can provide an accurate diagnosis and determine the appropriate course of treatment. To ensure the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory, as different laboratories may use varying methods and units of measurement for similar tests.
Preparation:
- informing the physician and medical staff about the medications being taken, particularly anticoagulant and antiplatelet medications;
- informing the physician about known conditions that may affect blood coagulation;
- following the physician’s recommendations regarding preparation for sample collection;
- do not discontinue any medications without the physician’s recommendation;
- additional recommendations may be provided by the physician depending on the indication for the examination.