Dehydroepiandrosterone sulfate, DHEA-S

DHEA-S

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

DHEA-S (Dehydroepiandrosterone sulfate) is a hormone produced by the adrenal glands. It is a metabolite of the hormone DHEA, which is a precursor to both male and female sex hormones. DHEA-S is the most abundant circulating hormone in the human body.

Functions and Significance

DHEA-S plays a crucial role in various physiological processes, including:

• Regulation of the immune system
• Maintenance of bone density
• Cardiovascular health
• Cognitive function
• Mood and well-being

DHEA-S levels typically decline with age, and this decline is associated with various age-related conditions, such as osteoporosis, cardiovascular disease, and cognitive decline.

DHEA-S Production and Regulation

The production of DHEA-S is regulated by the hypothalamic-pituitary-adrenal (HPA) axis. The levels of DHEA-S can vary depending on various factors, including:

It is essential to maintain optimal levels of DHEA-S for overall health and well-being. However, interpreting DHEA-S levels should be done under the guidance of a qualified healthcare professional, as various factors can influence its levels.

The Role of DHEA-S in Diagnostics

Dehydroepiandrosterone sulfate (DHEA-S) is an important hormone produced by the adrenal glands. It serves as a precursor for the synthesis of other hormones, including testosterone and estrogen. Measuring DHEA-S levels in the blood can provide valuable information about adrenal gland function and hormonal balance.

Indications for DHEA-S Testing

The DHEA-S test is often ordered to evaluate the following conditions:

• Adrenal gland disorders: DHEA-S levels can help diagnose conditions such as adrenal insufficiency (Addison's disease) or congenital adrenal hyperplasia, which can affect hormone production.
• Polycystic ovary syndrome (PCOS): Women with PCOS may have elevated DHEA-S levels due to increased androgen production.
• Hirsutism (excessive hair growth): High DHEA-S levels can contribute to increased hair growth in women.
• Hormone imbalances: DHEA-S testing may be performed to assess hormonal imbalances, particularly in older individuals, as DHEA-S levels naturally decline with age.

Preparation for the DHEA-S Test Procedure

The procedure for a DHEA-S blood test is relatively simple and does not require special preparation. However, there are a few recommendations to consider:

• Diet: You can typically take the DHEA-S test with or without fasting, but in some cases (e.g., when combined with other tests), an 8-12 hour fast may be required.
• Physical activity: Avoid intense physical activity before the test, as it may affect the results.
• Alcohol and smoking: Refrain from alcohol consumption and smoking for at least 24 hours before the test, as these can influence hormone levels.
• Hydration: Maintain proper hydration to facilitate the blood draw process.
• Medications: Inform your healthcare provider about any medications you are taking, as some may affect DHEA-S levels.

DHEA-S Test Procedure

The DHEA-S test typically involves drawing a small amount of blood from a vein, usually in the arm. The procedure is quick and performed by a trained healthcare professional. You may experience minor bleeding or bruising at the puncture site, which typically resolves within a few days.

Sources:

https://www.mountsinai.org/health-library/tests/dhea-sulfate-test
https://www.healthline.com/health/dhea-sulfate-serum
https://medlineplus.gov/lab-tests/dhea-sulfate-test/
https://www.webmd.com/healthy-aging/aging-dhea-test
https://www.testing.com/tests/dheas/
https://my.clevelandclinic.org/health/diagnostics/22148-dheas-test-dhea-sulfate-test
https://www.rupahealth.com/post/how-to-interpret-your-dheas-test-results
https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.dhea-s-test.abp5017

Important!

It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any symptoms or a worsening of a condition, it is essential to consult a healthcare professional for proper diagnostic testing and treatment. Only a qualified specialist can accurately diagnose and determine the appropriate treatment. To obtain the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory, as different laboratories may use varying methods and units of measurement for similar tests.