Free estriol, E3

E3

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

E3 (Estrone) is a steroid hormone that belongs to the estrogen group. It is a relatively weak estrogen produced primarily by the ovaries in premenopausal women and by the peripheral conversion of androstenedione in postmenopausal women and men. E3 plays a crucial role in various physiological processes, including the regulation of the menstrual cycle, development of female reproductive organs, and maintenance of bone health.

Structure and Functions of E3

E3 is a C18 steroid hormone with a characteristic phenolic ring structure. Its molecular structure allows it to bind to estrogen receptors, which are present in various tissues throughout the body, including the reproductive organs, bones, brain, and cardiovascular system.

E3 plays a vital role in maintaining the female reproductive system and regulating various physiological processes. It contributes to the development and maturation of the ovarian follicles, supports the uterine lining during the menstrual cycle, and prepares the body for potential pregnancy. Additionally, E3 is involved in bone metabolism, helping to maintain bone density and strength.

Role of E3"

E3" plays a crucial role in various physiological processes within the human body. It is an essential component involved in various metabolic pathways and cellular functions.

Indications for E3" Testing

E3" testing is recommended in several situations to aid in the diagnosis and monitoring of various health conditions. The primary indications for E3" testing include:

• Screening for metabolic disorders: Abnormal levels of E3" may indicate an underlying metabolic condition, such as enzyme deficiencies or inherited metabolic disorders.
• Monitoring treatment response: E3" levels are monitored in patients undergoing treatment for certain conditions to assess the effectiveness of the therapy.
• Evaluation of organ function: Levels of E3" can provide insights into the functional status of specific organs, such as the liver or kidneys.
• Routine health check-ups: E3" testing may be included as part of routine health screenings to identify any potential imbalances or abnormalities.

Preparation for the Analysis Procedure

The procedure for giving blood to determine the E3" level is relatively simple and does not require any special preparation measures. However, there are a few recommendations to consider:

• Maintain a regular diet: In most cases, the E3" blood test can be taken either on an empty stomach or after a meal. However, in some situations (e.g., during a comprehensive biochemical blood test), an 8-12 hour fast before the blood draw may be required.
• Avoid physical exertion: It is advisable to avoid strenuous physical activity on the day before the test, as it may affect the results of the analysis.
• Abstain from alcohol and smoking: It is recommended to refrain from consuming alcohol and smoking for a day before the test, as these activities can influence the E3" level and other blood parameters.
• Maintain proper hydration: Adequate hydration is important to facilitate the blood draw process. Insufficient fluid intake can make the venipuncture procedure more difficult.
• Inform your doctor about medications: Some medications can affect the E3" level and other blood parameters. Therefore, it is essential to inform your doctor about all medications you are taking.

The Analysis Procedure

The blood draw for the E3" analysis is typically performed from a vein in the arm, usually at the elbow crease. The procedure takes a few minutes and is carried out by a medical professional. After the venipuncture, some minor bleeding or bruising may occur, but it usually resolves on its own within a few days.

About E3 Analysis

The E3 analysis, also known as the estriol test, is a routine prenatal screening test that measures the level of the hormone estriol in a pregnant woman's blood or urine. Estriol is one of the three main estrogens produced during pregnancy, with the placenta being the primary source of this hormone.

The estriol level is typically measured between the 15th and 20th week of pregnancy, or during the second trimester. This analysis is often included as part of a triple or quadruple screening test, which also measures other hormones and proteins to assess the risk of certain birth defects or chromosomal abnormalities.

The estriol test is an essential part of prenatal care as it can provide valuable information about the well-being of the pregnancy and the developing fetus. Abnormal levels of estriol may indicate potential complications or risks, such as placental problems, fetal distress, or chromosomal disorders like Down syndrome.

Sources:

https://pubmed.ncbi.nlm.nih.gov/28375935/
https://testdirectory.questdiagnostics.com/test/test-detail/36169/estradiol-free?cc=MASTER
https://en.wikipedia.org/wiki/Estriol
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939441/
https://labs.selfdecode.com/blog/estriol-blood-test-high-low-levels-normal-range/
https://my.clevelandclinic.org/health/articles/22399-estriol
https://endocrinology.testcatalog.org/show/UE3

IMPORTANT!

It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any pain or exacerbation of a condition, it is essential to consult a healthcare professional for proper diagnostic testing and treatment. Only a qualified specialist can provide an accurate diagnosis and determine the appropriate treatment. To ensure the most accurate and consistent evaluation of test results, it is recommended to have them conducted at the same laboratory. This is because different laboratories may use varying methods and units of measurement for similar tests.