Immunoglobulin E, IgE total
1 day 
Available with home visit We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.
Total Immunoglobulin E (Total IgE) is a marker that reflects the overall activity of the immune system related to allergic reactions and the body's defense against certain parasitic infections. An elevated total IgE level may indicate an allergic predisposition; however, it does not identify the specific allergen responsible.
The test is used as a complementary tool in the diagnosis of allergic diseases and helps the physician determine whether additional allergy testing, including allergen-specific IgE assays, is required.
Indications
The test is recommended for individuals with:
- suspected allergic diseases;
- allergic rhinitis (hay fever);
- allergic bronchial asthma;
- atopic dermatitis;
- food allergy;
- chronic urticaria;
- suspected parasitic infections;
- assessment of allergic predisposition;
- recurrent allergic symptoms.
What does the test show?
Immunoglobulin E (IgE) is an antibody involved in immediate hypersensitivity reactions. When the body is exposed to an allergen, it produces IgE antibodies that bind to mast cells and basophils. Upon subsequent exposure to the same allergen, histamine and other biologically active substances are released, causing symptoms such as itching, sneezing, runny nose, skin rash, swelling, and breathing difficulties.
It is important to note that total IgE does not identify the specific allergen responsible for the allergic reaction. Additional testing for allergen-specific IgE or molecular allergen components may be required to determine the cause of the allergy.
Procedure
The test is performed using a venous blood sample.
The laboratory measures the concentration of total Immunoglobulin E (IgE) in the blood serum. The test is safe and does not require the patient to be exposed to allergens.
Sources:
https://medlineplus.gov/lab-tests/allergy-blood-test/
https://dermnetnz.org/topics/immunoglobulin-e-tests
https://my.clevelandclinic.org/health/treatments/22345-allergy-blood-test
https://labs.selfdecode.com/blog/immunoglobulin-e-ige-antibody-test/
https://www.verywellhealth.com/ige-test-overview-6362110
https://www.testing.com/tests/total-ige/
https://www.verywellhealth.com/immunoglobulin-e-ige-5324765
IMPORTANT!
It's crucial to remember that the information provided here is not intended for self-diagnosis or self-treatment. If you experience any symptoms or have a medical condition, it's essential to consult a qualified healthcare professional for proper diagnosis and treatment. Only a licensed physician can make an accurate diagnosis and recommend appropriate treatment. For consistent and accurate evaluation of test results, it's recommended to have the tests performed at the same laboratory, as different laboratories may use varying methods and units of measurement for similar tests.
Preparation:
No special preparation is required.
For the most reliable results, it is recommended to:
- have the blood sample collected while fasting or at least 3–4 hours after a light meal;
- avoid strenuous physical activity and alcohol consumption the day before testing;
- avoid smoking, physical exertion, and emotional stress for at least 30 minutes before blood collection;
- rest quietly for 10–15 minutes before the blood draw.
The use of antihistamines generally does not affect total IgE levels and usually does not need to be discontinued before testing. If the patient is receiving corticosteroids or immunosuppressive therapy, this should be reported to the physician for appropriate interpretation of the results.
You may also be interested in:
1 day 1 day 1 day 2 days 2 days 
