Neisseria gonorrhoeae (DNA, qualitative)

Neisseria Gonorrhoeae (DNA- Qualitative)

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

Neisseria gonorrhoeae is a gram-negative, non-motile, and non-spore-forming bacterium that causes the sexually transmitted infection (STI) gonorrhea. It is a human-specific pathogen that primarily infects the mucous membranes of the reproductive tract, including the cervix, uterus, and fallopian tubes in women, and the urethra in men. Gonorrhea can also infect the rectum, throat, and eyes.

Structure and Pathogenesis

Neisseria gonorrhoeae is a diplococcus, meaning it occurs in pairs of oval-shaped cells. It possesses pili, which are hair-like appendages that facilitate attachment to host cells, and a lipopolysaccharide-containing outer membrane that contributes to its pathogenicity. The bacterium can survive within host cells, evading the immune system and antibiotics.

Neisseria gonorrhoeae can cause inflammation and tissue damage in the infected areas, leading to various symptoms such as discharge, pain, and, in severe cases, disseminated gonococcal infection (DGI), which can involve the bloodstream and other organs.

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Role of Neisseria Gonorrhoeae (DNA-Qualitative) Test

The Neisseria Gonorrhoeae (DNA-Qualitative) test is a molecular diagnostic tool used to detect the presence of the Neisseria gonorrhoeae bacteria, which is the causative agent of gonorrhea. This test plays a crucial role in the accurate diagnosis of gonorrheal infections, enabling prompt treatment and preventing further transmission.

Indications for Ordering the Test

The Neisseria Gonorrhoeae (DNA-Qualitative) test is recommended in the following situations:

• Evaluation of individuals with symptoms suggestive of gonorrheal infection, such as genital discharge, pelvic pain, or urinary discomfort.
• Screening of high-risk populations, including individuals with multiple sexual partners, sex workers, and individuals who engage in unprotected sexual intercourse.
• Testing of asymptomatic individuals as part of routine screening programs, particularly in specific settings like prenatal care or correctional facilities.
• Follow-up testing after treatment to confirm successful clearance of the infection.
• Investigation of potential sexual partners of individuals diagnosed with gonorrhea to identify and treat additional cases.

Preparation for the Analysis Procedure

For the Neisseria Gonorrhoeae (DNA-Qualitative) analysis, no special preparation is typically required. However, it is recommended to follow these guidelines:

• Hydration: Maintain proper hydration before the test to facilitate the sample collection process.
• Medications: Inform your healthcare provider about any medications you are taking, as some may potentially interfere with the test results.
• Recent activities: Avoid any activities that may affect the sample or introduce contamination before the test.

Analysis Procedure

The Neisseria Gonorrhoeae (DNA-Qualitative) analysis typically involves collecting a sample from the appropriate site (e.g., urethra, cervix, throat, or rectum) using a swab or other approved collection method. The procedure is generally quick and minimally invasive.

Sources:

https://medlineplus.gov/lab-tests/gonorrhea-test/
https://my.clevelandclinic.org/health/diagnostics/25211-gonorrhea-test
https://www.who.int/news-room/fact-sheets/detail/gonorrhoea-(neisseria-gonorrhoeae-infection)#:~:text=Key%20facts,new%20infections%20among%20adults%20globally.
https://www.mayoclinic.org/diseases-conditions/gonorrhea/symptoms-causes/syc-20351774

IMPORTANT!

It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any symptoms or have concerns about an illness, it is essential to consult a healthcare professional for proper diagnosis and treatment. Only a qualified specialist can accurately assess your condition and provide appropriate medical care. To ensure the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory, as different laboratories may use varying methods and units of measurement for similar tests.