PrenaTest STANDARD 1 (trisomy 21)

Prenatest Standard 1 (Trisomy 21)

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

Prenatest Standard 1 is a non-invasive prenatal screening test that analyzes cell-free DNA (cfDNA) from the mother's blood to evaluate the risk of the fetus having Trisomy 21 (Down syndrome). This screening test provides an accurate assessment of the risk for this chromosomal condition, allowing for informed decision-making and further diagnostic testing if needed.

Cell-free DNA and Trisomy 21 Screening

During pregnancy, a small amount of the fetus's DNA circulates in the mother's bloodstream. This cell-free fetal DNA (cffDNA) is derived from the placenta and can be analyzed to detect potential chromosomal abnormalities, such as Trisomy 21, which is caused by the presence of an extra copy of chromosome 21.

By analyzing the cffDNA in the mother's blood sample, the Prenatest Standard 1 test can determine the risk of the fetus having Trisomy 21 with a high degree of accuracy.

The Prenatest Standard 1 test provides valuable information to expectant parents, allowing them to make informed decisions about further diagnostic testing or preparation for the potential birth of a child with Down syndrome.

Role of Prenatest Standard 1 (Trisomy 21) in Diagnostics

Prenatest Standard 1 (Trisomy 21) is a non-invasive prenatal screening test designed to detect the risk of Down syndrome (Trisomy 21) and other chromosomal abnormalities in the developing fetus. This test analyzes cell-free fetal DNA (cffDNA) present in the maternal blood sample. By assessing the relative amounts of specific chromosomal sequences, the test can estimate the likelihood of the fetus having Down syndrome or other chromosomal conditions.

Indications for Ordering Prenatest Standard 1 (Trisomy 21)

The Prenatest Standard 1 (Trisomy 21) screening is typically recommended for pregnant women, particularly those with an increased risk of having a child with Down syndrome or other chromosomal abnormalities. Indications for ordering this test may include:

• Advanced maternal age (typically over 35 years old)
• Abnormal results from other prenatal screening tests (e.g., first-trimester screening, ultrasound findings)
• Family history of chromosomal disorders
• Previous pregnancy with a chromosomal abnormality

Preparation for the procedure

The preparation for the Prenatest Standard 1 (Trisomy 21) test is relatively simple and does not require any special measures. However, there are a few recommendations to consider:

• Hydration: It is important to maintain proper hydration levels before the test, as dehydration can affect the accuracy of the results.
• Medication: Inform your healthcare provider about any medications or supplements you are taking, as some substances may interfere with the test results.
• Fasting: In most cases, there is no need to fast before the test. However, your healthcare provider may provide specific instructions if fasting is required.

Procedure

The Prenatest Standard 1 (Trisomy 21) test involves collecting a blood sample from a vein, typically in your arm. The procedure is quick and performed by a trained medical professional. Some mild discomfort or bruising may occur at the puncture site, but it should resolve within a few days.

About Prenatest Standard 1 (Trisomy 21)

Prenatest Standard 1 (Trisomy 21) is a non-invasive prenatal screening test that analyzes cell-free DNA (cfDNA) from the mother's blood to assess the risk of the fetus having Trisomy 21, also known as Down syndrome. It is typically performed during the first trimester of pregnancy, usually between 10 and 22 weeks of gestation.

The test works by measuring the relative amounts of specific chromosomal fragments present in the maternal blood, which can indicate the presence or absence of certain chromosomal aneuploidies, including Trisomy 21. The analysis is performed by advanced biochemical and molecular techniques, such as Next-Generation Sequencing (NGS) or Massively Parallel Sequencing (MPS).

This screening test provides valuable information about the potential risk of Trisomy 21, allowing expectant parents and healthcare providers to make informed decisions about further diagnostic testing or pregnancy management. However, it is important to note that the Prenatest Standard 1 (Trisomy 21) is a screening test and not a diagnostic test, meaning that it cannot definitively confirm or rule out the presence of Trisomy 21.

Sources:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328480/
https://en.wikipedia.org/wiki/Prenatal_testing
https://www.webmd.com/baby/your-guide-prenatal-testing

IMPORTANT!

It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any pain or exacerbation of a condition, it is essential to consult a healthcare professional for proper diagnostic tests and treatment. Only a qualified specialist can make an accurate diagnosis and determine the appropriate treatment. To ensure the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may use varying methods and units of measurement for conducting similar tests.