Thrombin time (TT)

Thrombin Time (TT) is a laboratory test used to assess the final stage of blood coagulation, during which fibrinogen is converted into fibrin under the action of thrombin. The test measures the time required for clot formation after the addition of a standardized amount of thrombin to the patient’s plasma.

The result may be influenced by the level and function of fibrinogen, the presence of fibrin degradation products, as well as certain anticoagulant medications, particularly heparin.

Indications

• assessment of the final stage of the blood coagulation process;
• investigation of bleeding of unclear origin;
• evaluation of quantitative or qualitative fibrinogen disorders;
• suspected presence of coagulation inhibitors;
• assessment of the anticoagulant effect of heparin, as recommended by a physician;
• monitoring of conditions or treatments that may affect fibrin formation;
• other clinical situations, as recommended by a physician.

Procedure

The test is performed using a venous blood sample. The time required for clot formation after the addition of a standardized amount of thrombin is determined in the plasma obtained from the sample.

Sources:

https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=thrombin_time
https://en.wikipedia.org/wiki/Thrombin_time
https://myhealth.ucsd.edu/Library/TestsProcedures/167,thrombin_time

IMPORTANT!

It is crucial to remember that the information provided here is not intended for self-diagnosis or self-treatment. If you experience any symptoms or a flare-up of an existing condition, it is essential to seek medical attention and consult a healthcare professional for diagnostic tests and proper treatment. Only a qualified specialist can make an accurate diagnosis and determine the appropriate course of treatment. To obtain the most accurate and consistent assessment of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may employ varying methods and units of measurement for similar tests.